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FAQ

What is BPC-157?

Quick Answer

BPC-157 is a synthetic 15-amino acid peptide fragment derived from human gastric juice protein, studied for tissue repair via VEGF upregulation and nitric oxide modulation.

Detailed Explanation

BPC-157 (Body Protection Compound-157) is a pentadecapeptide with the sequence Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val. It was first isolated from human gastric juice and has been studied extensively in preclinical tissue repair models. Its primary mechanisms include VEGF upregulation for angiogenesis, FAK-paxillin pathway activation for cell adhesion, and nitric oxide system modulation. Research has also demonstrated interactions with dopaminergic, serotonergic, and GABAergic neurotransmitter systems. BPC-157 is notable for its stability in acidic conditions (pH 2–7), distinguishing it from most peptides.

Related Research & Documentation

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